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KMID : 0360219700110040049
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Journal of the Korean Ophthalmological Society
1970 Volume.11 No. 4 p.49 ~ p.54
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Mydriatic Action of Phenylephrine Hydrochloride
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Abstract
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Phenylephrine hydrochloride has been widely used in ocular therapy and examination, such as the treatment of uveitis and glaucoma and examination of the eye ground. In this study, mydriatic action of single instillation of 10% phenylephrine hydrochloride solution was compared with that of combined instillation of 10% phenylephrine hydrochloride solution and 0.5% tetracaine drops in 110 brown eyes.
The following results were obtained;
1). In 55 eyes, the diameter of the pupil reached more than 7mm about 45 minutes after instillation of 10% phenylephrine hydrochloride solution.
2) In case of combined instillation of 0.5% tetracaine solution and 10% phenylephrine hydrochloride solution, the onset of mydriasis´ was delayed.
3) In the case of combined instillation of 0.5% tetracaine and 10% phenylephrine hydrochloride solution with 5 and 10 minutes interval, the action of mydriasis was accelerated.
4) After tonometry, the action of mydriasis was more accelerated.
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